Scientific updates, studies and expert articles from aesthetic medicine — curated by MEDEMIE.
New articles regularly.
Nodules, swelling and redness weeks or months after a filler treatment are rare but hard to predict. A meta-analysis of 242 studies quantifies the incidence for the first time – with limitations you should know.
Physicians, dentists, Heilpraktiker (non-medical practitioners), beauticians: who may inject botulinum toxin and hyaluronic acid fillers? The legal situation in Germany with statutes, court rulings and open questions – as of October 2026.
Semaglutide and tirzepatide also change the face. A prospective study has examined what PLLA plus hyaluronic acid can achieve after weight loss – and where the data end.
With the menopause, the skin loses collagen, thickness and elasticity. A meta-analysis of 15 studies has examined what hormone therapy changes about this – with figures and a critical appraisal.
Peptides are one of the major topics in aesthetics. The best studied are oral collagen peptides: a meta-analysis of 26 randomised trials shows what measurable effects they have – and what remains open.
Approval of a ready-to-use liquid botulinum toxin in Germany: an overview of the phase III data on frown lines and crow's feet.
Combining energy-based devices and hyaluronic acid fillers: how heat affects the filler and what to bear in mind when combining them.
Treating masseter hypertrophy with botulinum toxin: clinical considerations and procedure for contouring the lower face.
Robot-assisted filler injections in the face: development, state of the art, and advantages and disadvantages at a glance.
Does intensive exercise affect the effect of botulinum toxin? A controlled single-blind study on efficacy at different levels of physical activity.
Horizontal forehead lines with botulinum toxin: what the anatomy of the frontalis (Yi et al. 2023) means for the injection points – and for the risk of ptosis.
Nose correction with hyaluronic acid and later surgery: what non-surgical rhinoplasty means for a subsequent surgical rhinoplasty.
Treating the temple with hyaluronic acid filler: which fascial layers the needle penetrates, which injection depths are discussed and what follows from this.
Does COVID-19 mRNA vaccination affect the efficacy of botulinum toxin? A retrospective cohort study (Azzam et al. 2022) and its relevance for practice.
Lips with hyaluronic acid: vertical or horizontal injection technique? Lip anatomy and what follows from it for safe, effective treatment.
Treating the platysma and jawline with botulinum toxin: anatomy of the platysma muscle, platysmal bands and injection points – expert article for physicians.
Reconstituting botulinum toxin with preserved or unpreserved saline? The evidence on patient comfort, efficacy and preparation.
Microbotox, baby Botox, mesobotox: intradermal injection of minute amounts of botulinum toxin – effect on pores, sebum production and skin appearance, evidence.
Botulinum toxin type A for unilateral cleft lip scars: a randomised double-blind study with 64 infants compares different injection points.
The Zoom effect: a Google Trends analysis examines how video calls during the pandemic changed interest in aesthetic procedures on the face.
Higher doses of botulinum toxin type A in the glabella: a systematic review examines whether the effect lasts longer and how safe the approach is.
Retrograde or bolus injection of botulinum toxin? A study (Labbe et al. 2021) compares the two techniques for glabellar lines, crow's feet and forehead lines.
Botulinum toxin type A and surgical scars: a randomised split-scar study (Chen et al. 2021) compares different doses.
Hyaluronidase in aesthetic medicine - new findings and treatment protocol.
Coverage of treatment costs by statutory health insurance for a Botox treatment?
Hyaluronic acid fillers and the extracellular matrix: studies show more collagen and elastin after injection – more than a pure volume effect?
Botulinum toxin in androgenetic alopecia: presumed mechanism of action, the evidence and an appraisal of off-label use for hair loss.
3 instead of 5 injection points in the treatment of glabellar lines with the neuromodulator botulinum toxin (Botox) - effective, safe and anatomically sound?
From the pigments of the Neanderthals to Leonardo's division of the face into thirds: brief facts on the history of aesthetics and aesthetic medicine.
EU Medical Device Regulation (MDR) and dermal fillers: what changes in approval and labelling – and what that means for everyday practice.
How face masks change the way we look at the face: a study on eye movement patterns and what it means for the perception of the face.
Aspiration before filler injection – yes or no? The arguments from the review by Goodman et al. (2021) and what they mean for safe injection.
Counterfeit products for wrinkle injection treatment: in a US survey around 41% of respondents had encountered counterfeits – results and consequences for practice.
Swelling after SARS-CoV-2 vaccination in patients with dermal fillers: what is known from the approval trial and what the FDA and ASDS recommend.