MEDEMIE – News & expert articles on aesthetic medicine https://medemie.de/en/news/ Studies, guides and expert articles on aesthetic medicine for physicians. en Mon, 12 Oct 2026 08:00:00 GMT Delayed inflammatory reactions after hyaluronic acid fillers: how common are they? A meta-analysis of 242 studieshttps://medemie.de/en/blog/spaete-entzuendungsreaktionen-hyaluronsaeure-filler-metaanalyse-49/https://medemie.de/en/blog/spaete-entzuendungsreaktionen-hyaluronsaeure-filler-metaanalyse-49/Mon, 12 Oct 2026 08:00:00 GMTDelayed inflammatory reactions after hyaluronic acid fillers: meta-analysis of 242 studies on incidence, onset, course and treatment – critically appraised. GOÄ billing for Botox and hyaluronic acid: codes & ruleshttps://medemie.de/en/blog/botox-hyaluron-goae-abrechnung/https://medemie.de/en/blog/botox-hyaluron-goae-abrechnung/Mon, 12 Oct 2026 08:00:00 GMTBilling botulinum toxin and hyaluronic acid fillers under GOÄ: codes 267 and 268, fee agreement, material costs, invoice and VAT – with sources. Additional qualification (Zusatzbezeichnung) in aesthetic medicine: what applies?https://medemie.de/en/blog/zusatzbezeichnung-aesthetische-medizin/https://medemie.de/en/blog/zusatzbezeichnung-aesthetische-medizin/Mon, 12 Oct 2026 08:00:00 GMTIs there an additional qualification in “aesthetic medicine”? What the training regulations provide, what physicians may announce and what courts objected to. A good Botox or filler course? Checklist for doctorshttps://medemie.de/en/blog/checkliste-botox-filler-kurs-fuer-aerzte/https://medemie.de/en/blog/checkliste-botox-filler-kurs-fuer-aerzte/Sun, 11 Oct 2026 08:00:00 GMTHow do you recognise a good Botox or filler course? Ten criteria for physicians: group size, hands-on share, models, anatomy, complications. What does a Botox course for doctors cost? 2026 priceshttps://medemie.de/en/blog/botox-kurs-kosten-fuer-aerzte/https://medemie.de/en/blog/botox-kurs-kosten-fuer-aerzte/Sun, 11 Oct 2026 08:00:00 GMTWhat does a Botox course for physicians cost? Prices for online courses and hands-on workshops, what should be included and what is incurred in addition. Who may inject Botox and hyaluronic acid? The legal situation for physicians, dentists and Heilpraktiker (non-medical practitioners)https://medemie.de/en/blog/wer-darf-botox-und-hyaluron-spritzen-aerzte-zahnaerzte-heilpraktiker-47/https://medemie.de/en/blog/wer-darf-botox-und-hyaluron-spritzen-aerzte-zahnaerzte-heilpraktiker-47/Sat, 10 Oct 2026 08:00:00 GMTWho may inject botulinum toxin and hyaluronic acid fillers? Legal position 2026 for physicians, dentists, Heilpraktiker and beauticians – with laws and rulings. GLP-1 receptor agonists and facial volume: PLLA plus hyaluronic acid after weight losshttps://medemie.de/en/blog/glp-1-gewichtsverlust-gesichtsvolumen-plla-hyaluronsaeure-studie-44/https://medemie.de/en/blog/glp-1-gewichtsverlust-gesichtsvolumen-plla-hyaluronsaeure-studie-44/Sat, 10 Oct 2026 08:00:00 GMTFirst prospective study on treating volume loss after GLP-1 therapy: PLLA plus hyaluronic acid in 41 people – results, measurements and limitations. Menopause and skin: what hormone therapy does for collagen, skin thickness and elasticityhttps://medemie.de/en/blog/menopause-haut-hormontherapie-kollagen-hautdicke-elastizitaet-metaanalyse-45/https://medemie.de/en/blog/menopause-haut-hormontherapie-kollagen-hautdicke-elastizitaet-metaanalyse-45/Sat, 10 Oct 2026 08:00:00 GMTMeta-analysis of 15 studies with 1,589 women: how menopausal hormone therapy affects collagen, skin thickness, elasticity and wrinkles – critically assessed. Oral collagen peptides: what 26 randomised trials show for skin hydration and elasticityhttps://medemie.de/en/blog/kollagenpeptide-haut-metaanalyse-hautfeuchtigkeit-elastizitaet-46/https://medemie.de/en/blog/kollagenpeptide-haut-metaanalyse-hautfeuchtigkeit-elastizitaet-46/Sat, 10 Oct 2026 08:00:00 GMTPeptides in aesthetics: meta-analysis of 26 randomised studies on collagen peptides – effects on skin hydration and elasticity, critically assessed. Galderma receives approval for Relfydess™ in Germany: first ready-to-use liquid neuromodulator for the treatment of frown lines and crow's feethttps://medemie.de/en/blog/galderma-erhlt-zulassung-fr-relfydess-in-deutschland-erster-gebrauchsfertiger-flssiger-neuromodulator-zur-behandlung-von-zornesfalten-und-krhenfssen-43/https://medemie.de/en/blog/galderma-erhlt-zulassung-fr-relfydess-in-deutschland-erster-gebrauchsfertiger-flssiger-neuromodulator-zur-behandlung-von-zornesfalten-und-krhenfssen-43/Fri, 22 Nov 2024 08:00:00 GMTApproval of a ready-to-use liquid botulinum toxin in Germany: an overview of the phase III data on frown lines and crow's feet. Combination therapy: energy-based devices and hyaluronic acid fillershttps://medemie.de/en/blog/kombinationstherapie-energiebasierte-gerte-und-hyaluronsure-fille-42/https://medemie.de/en/blog/kombinationstherapie-energiebasierte-gerte-und-hyaluronsure-fille-42/Sun, 05 May 2024 08:00:00 GMTCombining energy-based devices and hyaluronic acid fillers: how heat affects the filler and what to bear in mind when combining them. Contouring the lower face and the masseter muscle: a minimally invasive solution with botulinum for a more feminine facehttps://medemie.de/en/blog/konturierung-des-untergesichts-und-des-massetermuskels-eine-minimal-invasive-lsung-mit-botulinum-fr-ein-feminineres-gesicht-41/https://medemie.de/en/blog/konturierung-des-untergesichts-und-des-massetermuskels-eine-minimal-invasive-lsung-mit-botulinum-fr-ein-feminineres-gesicht-41/Wed, 21 Feb 2024 08:00:00 GMTTreating masseter hypertrophy with botulinum toxin: clinical considerations and procedure for contouring the lower face. The future of aesthetics: robotics in facial injections?https://medemie.de/en/blog/die-zukunft-der-sthetik-robotik-innovationen-bei-gesichtsfiller-injektionen-40/https://medemie.de/en/blog/die-zukunft-der-sthetik-robotik-innovationen-bei-gesichtsfiller-injektionen-40/Wed, 06 Dec 2023 08:00:00 GMTRobot-assisted filler injections in the face: development, state of the art, and advantages and disadvantages at a glance. Fit rather than wrinkle-free? How intense physical activity could influence the efficacy of botulinum toxin – findings from a controlled single-blind studyhttps://medemie.de/en/blog/fit-statt-faltenfrei-wie-intensive-krperliche-aktivitt-die-wirksamkeit-von-botulinumtoxin-beeinflussen-knnte-erkenntnisse-aus-einer-kontrollierten-einfachblindstudie-38/https://medemie.de/en/blog/fit-statt-faltenfrei-wie-intensive-krperliche-aktivitt-die-wirksamkeit-von-botulinumtoxin-beeinflussen-knnte-erkenntnisse-aus-einer-kontrollierten-einfachblindstudie-38/Wed, 09 Aug 2023 08:00:00 GMTDoes intensive exercise affect the effect of botulinum toxin? A controlled single-blind study on efficacy at different levels of physical activity. Anatomical proposal for the injection of botulinum neurotoxin for horizontal forehead lineshttps://medemie.de/en/blog/anatomischer-vorschlag-fr-die-injektion-von-botulinum-neurotoxin-bei-horizontalen-stirnfalten-37/https://medemie.de/en/blog/anatomischer-vorschlag-fr-die-injektion-von-botulinum-neurotoxin-bei-horizontalen-stirnfalten-37/Fri, 23 Jun 2023 08:00:00 GMTHorizontal forehead lines with botulinum toxin: what the anatomy of the frontalis (Yi et al. 2023) means for the injection points – and for the risk of ptosis. Surgical rhinoplasty after hyaluronic acid nose reshapinghttps://medemie.de/en/blog/chirurgische-rhinoplastik-nach-vorheriger-nasaler-umgestaltung-mit-hyaluronsaure-35/https://medemie.de/en/blog/chirurgische-rhinoplastik-nach-vorheriger-nasaler-umgestaltung-mit-hyaluronsaure-35/Sun, 30 Apr 2023 08:00:00 GMTNose correction with hyaluronic acid and later surgery: what non-surgical rhinoplasty means for a subsequent surgical rhinoplasty. Treatment of the temple with hyaluronic acid filler: penetration force through the superficial and deep temporal fascia and implications for treatmenthttps://medemie.de/en/blog/behandlung-der-schlafe-mit-hyaluronsaure-filler-penetrationskraft-durch-die-oberflachliche-und-tiefe-schlafenfaszie-und-implikationen-fur-die-behandlung-34/https://medemie.de/en/blog/behandlung-der-schlafe-mit-hyaluronsaure-filler-penetrationskraft-durch-die-oberflachliche-und-tiefe-schlafenfaszie-und-implikationen-fur-die-behandlung-34/Sun, 22 Jan 2023 08:00:00 GMTTreating the temple with hyaluronic acid filler: which fascial layers the needle penetrates, which injection depths are discussed and what follows from this. Influence of COVID-19 mRNA vaccination on the efficacy and safety of botulinum toxin (Botox) treatmentshttps://medemie.de/en/blog/einfluss-der-covid-19-mrna-impfung-auf-die-wirksamkeit-und-sicherheit-von-botulinumtoxin-botox-behandlungen-33/https://medemie.de/en/blog/einfluss-der-covid-19-mrna-impfung-auf-die-wirksamkeit-und-sicherheit-von-botulinumtoxin-botox-behandlungen-33/Sun, 08 Jan 2023 08:00:00 GMTDoes COVID-19 mRNA vaccination affect the efficacy of botulinum toxin? A retrospective cohort study (Azzam et al. 2022) and its relevance for practice. Lip indication: vertical vs. horizontal injection technique with hyaluronic acid fillershttps://medemie.de/en/blog/indikation-lippe-vertikale-vs-horizontale-injektionstechnik-mit-hyaluronsaure-fillern-32/https://medemie.de/en/blog/indikation-lippe-vertikale-vs-horizontale-injektionstechnik-mit-hyaluronsaure-fillern-32/Wed, 04 Jan 2023 08:00:00 GMTLips with hyaluronic acid: vertical or horizontal injection technique? Lip anatomy and what follows from it for safe, effective treatment. Platysma muscle & Botox: anatomy and injection pointshttps://medemie.de/en/blog/jawline-und-platysma-halslifting-mit-botulinumtoxin-29/https://medemie.de/en/blog/jawline-und-platysma-halslifting-mit-botulinumtoxin-29/Thu, 29 Dec 2022 08:00:00 GMTTreating the platysma and jawline with botulinum toxin: anatomy of the platysma muscle, platysmal bands and injection points – expert article for physicians. Botulinum toxin: reconstitution with unpreserved vs. preserved physiological salinehttps://medemie.de/en/blog/botulinumtoxin-rekonstitution-mit-unkonservierter-vs-konservierter-physiologischer-kochsalzlosung-31/https://medemie.de/en/blog/botulinumtoxin-rekonstitution-mit-unkonservierter-vs-konservierter-physiologischer-kochsalzlosung-31/Thu, 29 Dec 2022 08:00:00 GMTReconstituting botulinum toxin with preserved or unpreserved saline? The evidence on patient comfort, efficacy and preparation. Microbotox (Micro-Botox): technique and evidencehttps://medemie.de/en/blog/mikrobotox-gesichtsverjungung-und-facelifting-28/https://medemie.de/en/blog/mikrobotox-gesichtsverjungung-und-facelifting-28/Sat, 05 Mar 2022 08:00:00 GMTMicrobotox, baby Botox, mesobotox: intradermal injection of minute amounts of botulinum toxin – effect on pores, sebum production and skin appearance, evidence. The effect of botulinum toxin type A on unilateral cleft lip scars: a comparison of different injection pointshttps://medemie.de/en/blog/die-wirkung-von-botulinumtoxin-typ-a-bei-einseitiger-lippenspaltnarbe-ein-vergleich-von-verschiedenen-injektionspunkten-26/https://medemie.de/en/blog/die-wirkung-von-botulinumtoxin-typ-a-bei-einseitiger-lippenspaltnarbe-ein-vergleich-von-verschiedenen-injektionspunkten-26/Tue, 18 Jan 2022 08:00:00 GMTBotulinum toxin type A for unilateral cleft lip scars: a randomised double-blind study with 64 infants compares different injection points. The Zoom effect: a Google Trends analysishttps://medemie.de/en/blog/der-zoom-effekt-eine-google-trends-analyse-25/https://medemie.de/en/blog/der-zoom-effekt-eine-google-trends-analyse-25/Thu, 28 Oct 2021 08:00:00 GMTThe Zoom effect: a Google Trends analysis examines how video calls during the pandemic changed interest in aesthetic procedures on the face. Higher dosing of botulinum toxin type A for glabellar lines – implications for efficacy and safetyhttps://medemie.de/en/blog/hhere-dosierung-von-botulinumtoxin-type-a-fr-die-glabellafalten-implikationen-fr-die-wirksamkeit-und-sicherheit-24/https://medemie.de/en/blog/hhere-dosierung-von-botulinumtoxin-type-a-fr-die-glabellafalten-implikationen-fr-die-wirksamkeit-und-sicherheit-24/Wed, 18 Aug 2021 08:00:00 GMTHigher doses of botulinum toxin type A in the glabella: a systematic review examines whether the effect lasts longer and how safe the approach is. Bolus or retrograde injection? Botulinum toxin techniquehttps://medemie.de/en/blog/retrograde-vs-bolus-injektion-von-botulinumtoxin-23/https://medemie.de/en/blog/retrograde-vs-bolus-injektion-von-botulinumtoxin-23/Wed, 04 Aug 2021 08:00:00 GMTRetrograde or bolus injection of botulinum toxin? A study (Labbe et al. 2021) compares the two techniques for glabellar lines, crow's feet and forehead lines. The influence of botulinum toxin injection dose on the appearance of surgical scarshttps://medemie.de/en/blog/der-einfluss-der-botulinumtoxin-injektionsdosis-auf-das-erscheinungsbild-chirurgischer-narben-22/https://medemie.de/en/blog/der-einfluss-der-botulinumtoxin-injektionsdosis-auf-das-erscheinungsbild-chirurgischer-narben-22/Sat, 17 Jul 2021 08:00:00 GMTBotulinum toxin type A and surgical scars: a randomised split-scar study (Chen et al. 2021) compares different doses. Hyaluronidase in aesthetic medicine – new treatment algorithmhttps://medemie.de/en/blog/hyaluronidase-in-der-sthetischen-medizin-neuer-behandlungsalgorithmus-21/https://medemie.de/en/blog/hyaluronidase-in-der-sthetischen-medizin-neuer-behandlungsalgorithmus-21/Wed, 07 Jul 2021 08:00:00 GMTHyaluronidase in aesthetic medicine: mode of action, off-label use for dissolving hyaluronic acid and a new treatment algorithm at a glance. Coverage of treatment costs by statutory health insurance for Botox treatment?https://medemie.de/en/blog/bernahme-der-behandlungskosten-durch-die-gesetzliche-krankenversicherung-bei-botulinumtoxin-botox-20/https://medemie.de/en/blog/bernahme-der-behandlungskosten-durch-die-gesetzliche-krankenversicherung-bei-botulinumtoxin-botox-20/Sat, 26 Jun 2021 08:00:00 GMTDoes health insurance pay for botulinum toxin? Not for aesthetic indications – for approved therapeutic indications it may bear the costs. A paradigm shift in the understanding of how hyaluronic acid fillers work?https://medemie.de/en/blog/paradigmenwechsel-im-verstndnis-der-wirkung-von-hyaluronsurefillern-19/https://medemie.de/en/blog/paradigmenwechsel-im-verstndnis-der-wirkung-von-hyaluronsurefillern-19/Sat, 19 Jun 2021 08:00:00 GMTHyaluronic acid fillers and the extracellular matrix: studies show more collagen and elastin after injection – more than a pure volume effect? Botulinum toxin and androgenetic alopecia (pattern hair loss)?https://medemie.de/en/blog/botulinumtoxin-und-androgenetische-alopezie-anlagebedingter-haarausfall-18/https://medemie.de/en/blog/botulinumtoxin-und-androgenetische-alopezie-anlagebedingter-haarausfall-18/Sun, 13 Jun 2021 08:00:00 GMTBotulinum toxin in androgenetic alopecia: presumed mechanism of action, the evidence and an appraisal of off-label use for hair loss. Three injection points in the treatment of glabellar lines with botulinum toxin – effective, safe and anatomically sound?https://medemie.de/en/blog/drei-anstatt-fnf-injektionspunkte-bei-der-behandlung-der-glabellafalten-durch-den-neuromodulator-botulinumtoxin-effektiv-sicher-und-anatomisch-sinnvoll-17/https://medemie.de/en/blog/drei-anstatt-fnf-injektionspunkte-bei-der-behandlung-der-glabellafalten-durch-den-neuromodulator-botulinumtoxin-effektiv-sicher-und-anatomisch-sinnvoll-17/Thu, 03 Jun 2021 08:00:00 GMTTreating glabellar lines with three instead of five injection points: the anatomical background and what this means for the efficacy and safety of treatment. Aesthetics fun factshttps://medemie.de/en/blog/sthetik-fun-facts-15/https://medemie.de/en/blog/sthetik-fun-facts-15/Tue, 11 May 2021 08:00:00 GMTFrom the pigments of the Neanderthals to Leonardo's division of the face into thirds: brief facts on the history of aesthetics and aesthetic medicine. What impact does the new EU Medical Device Regulation have on physicians’ day-to-day practice when using dermal fillers?https://medemie.de/en/blog/welche-auswirkungen-hat-die-neue-eu-medizinprodukteverordnung-bei-verwendung-von-dermalen-fillern-fr-den-praxisalltag-von-rzten-14/https://medemie.de/en/blog/welche-auswirkungen-hat-die-neue-eu-medizinprodukteverordnung-bei-verwendung-von-dermalen-fillern-fr-den-praxisalltag-von-rzten-14/Fri, 07 May 2021 08:00:00 GMTEU Medical Device Regulation (MDR) and dermal fillers: what changes in approval and labelling – and what that means for everyday practice. How does wearing a face mask influence the eye movement pattern during the COVID-19 pandemic?https://medemie.de/en/blog/wie-beeinflusst-das-tragen-eines-mundschutzes-das-augenbewegungsmuster-whrend-der-coid-19-pandemie-13/https://medemie.de/en/blog/wie-beeinflusst-das-tragen-eines-mundschutzes-das-augenbewegungsmuster-whrend-der-coid-19-pandemie-13/Sun, 02 May 2021 08:00:00 GMTHow face masks change the way we look at the face: a study on eye movement patterns and what it means for the perception of the face. Aspiration before the injection of dermal hyaluronic acid fillers - yes or no?https://medemie.de/en/blog/aspiration-vor-der-injektion-von-dermalen-hyaluronsure-fillern-ja-oder-nein-12/https://medemie.de/en/blog/aspiration-vor-der-injektion-von-dermalen-hyaluronsure-fillern-ja-oder-nein-12/Thu, 29 Apr 2021 08:00:00 GMTAspiration before filler injection – yes or no? The arguments from the review by Goodman et al. (2021) and what they mean for safe injection. Counterfeit medical devices for wrinkle injection treatment – a new surveyhttps://medemie.de/en/blog/produktflschungen-von-medizinprodukten-zur-faltenunterspritzung-eine-neue-umfrage-11/https://medemie.de/en/blog/produktflschungen-von-medizinprodukten-zur-faltenunterspritzung-eine-neue-umfrage-11/Sun, 18 Apr 2021 08:00:00 GMTCounterfeit products for wrinkle injection treatment: in a US survey around 41% of respondents had encountered counterfeits – results and consequences for practice. SARS-CoV-2 VACCINE & DERMAL FILLERS: complications and risks?https://medemie.de/en/blog/sars-cov-2-impfstoff-dermale-filler-komplikationen-und-risiken-10/https://medemie.de/en/blog/sars-cov-2-impfstoff-dermale-filler-komplikationen-und-risiken-10/Thu, 15 Apr 2021 08:00:00 GMTSwelling after SARS-CoV-2 vaccination in patients with dermal fillers: what is known from the approval trial and what the FDA and ASDS recommend.